Holt County is one of the largest in the State. It is bounded on the north by the Niobrara River, on the east by Knox and Antelope Counties, on the south by Wheeler County, and on the west by unorganized territory. It is forty-eight miles wide from east to west, and averages fifty and a fourth miles long from north to south, containing about 2,412 square miles, or 1,540,000 acres. There are but two counties larger in the State, Custer and Lincoln. Its boundary lines defined by statute are as follows: "Commencing at the southwest corner of Township 25 north, of Range 16 west; thence east to the southeast corner of Township 25 north, of Range 9 west; thence north to the middle of the main channel of the Niobrara River; thence up said channel to a point where the second guide meridian intersects the same; thence south along said guide meridian to the place of beginning."